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KMID : 0829320090120030103
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Korean Journal of Clinical Microbiology
2009 Volume.12 No. 3 p.103 ~ p.109
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Metallo-β-lactamase Producing Gram-negative Bacilli
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Yong Dong-Eun
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Abstract
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Among gram-negative bacteria, rate of antibiotic resistance has been increasing. As a result, carbapenem is now considered as a last resort of therapeutic regimens for gram-negative bacterial infections. The choice of antibiotics has been impeded by the spread of organisms producing metallo-β-lactamases (MBL), which can confer resistance to nearly all β-lactams. MBLs have extremely diverse structures and are carried by various organisms including human pathogens. This review will focus on the classification and current status of MBL reported in Korea.
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KEYWORD
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Metallo-β-lactamase, Gram-negative bacilli
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